He will be quizzed as part of topical questions as firms up and down the country warn about the devastating impact of the revaluation.
Shadow finance secretary Murdo Fraser has been selected to ask the Scottish Government what action it is taking on the matter.
The Scottish Conservatives last week demanded a statement by Mr Mackay amid accusations ministers have been slow act.
The SNP was warned last year there would be a “severe” impact on various industries if business rates changes go ahead.
However, it has taken until this week for Mr Mackay to respond formally in front of MSPs.
Scottish Conservative shadow finance secretary Murdo Fraser said:
“Businesses across Scotland want to hear what the Scottish Government is going to do about all this.
“Now we will have that chance in the Scottish Parliament.
“Firms that face going to the wall and people whose jobs are in jeopardy will be extremely interested in the answer.
“This is fast-becoming a crisis, affecting organisations large and small, and in all areas of the country.
“The SNP needs to take urgent action.”